The Endocannabinoid System

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mechoulam
The active compound that most associate with the cannabis plant is the THC or tetrahydrocannabinol. That compound was identified by Raphael Mechoulam in 1964. His research led to the discovery of what we know today as the EndoCannabinoid System. Our

Endocannabinoids Anandamide and 2-Arachidonyl-glycerol

Endocannabinoids Anandamide and 2-Arachidonyl-glycerol

bodies have a network of lock-and-key chemical receptors that respond to the “signals” of cannabinoids. We naturally produce the endogenous cannabinoids Anandamide and 2-Arachidonyl-glycerol (2AG). These compounds are found to naturally occur in mother’s breast-milk to help stimulate the infant’s appetite.

THC and other identified cannabinoids CBD, CBN, CBG, CBC and dozens more, are phytocannabinoids produced through photosynthesis in hair-like trichomes on the surface of the cannabis plants during flowering phase. (See left of illustration below) As an annual, cannabis plants follow a solar cycle consisting of two basic stages often referred to as vegetative, and bloom. Cannabinoids are created in the bloom phase. See Cannabis for more information.

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The Endocannabinoid System is currently the topic of some studies, mostly outside of the US, aimed at unlocking the mystery of overwhelming world-wide anecdotal reports of cannabis cures. CB1 receptors are concentrated in the brain and central nervous system but also sparsely populates other parts of the human body. CB2 receptors are mostly in the peripheral organs especially cells associated with the immune system. Using the plant compounds to modify our existing network of receptors has produced repeatedly positive results in the treatment of a considerable number of medical conditions including curing cancer!!!

rick and rso

Rick Simpson Click for more info

Concentrate made from the flowering tops of the cannabis plant can produce a viscous oil containing large doses of active cannabinoids. The process was first made popular by Rick Simpson and commonly called RSO or Phoenix Tears. The ratio of compounds are typically 45%-65% THC and 7% to 12% CBD. Cannabidiol has been shown to reduce the intense “high” side effects of THC including the altered consciousnesses,  confusion and anxiety. Patients with several different forms of cancer have been able to use this oil topically and internally to force cancerous cells to kill themselves. RSO has often had a higher success rate than chemotherapy and radiation therapies. While these traditional therapies destroy cancer cells, they also destroy healthy tissue indiscriminately. RSO kills only cancer cells and leaves healthy tissue intact giving the patient better chances of recovery. RSO has also been therapeutic for treatment of chronic pain, inflammation, muscle spasms, intestinal disorders and more. Play the video clip below to listen to professionals explain the ECS. Or watch the documentary “Clearing the Smoke: The Science of Cannabis”.

Below is a preview of “What if Cannabis Cured Cancer” by Len Richmond. You can buy a copy of the full documentary on Amazon.

Read More: Pubmed Search Cannabis + Cancer

Read More: Details on Cannabinoids

Read More: Pubmed ‘Cannabinoids, Endocannabinoids, and Cancer”

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One thought on “The Endocannabinoid System

  1. Excellent start for cannabis research, it truly shows that we are now understanding the chemistry that has been proven time after time in uses for thousands of years. As a nurse and patient it is important to have an easily found source for new people interested in this medication. Thanks again.

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